Vesicular exocytosis and microdevices – microelectrode arrays
نویسندگان
چکیده
منابع مشابه
Microelectrode Arrays
The development of implantable devices which enable fully wireless transmission of brain signals, recorded by microelectrode arrays (MEA) as dynamical neural circuit information, is one important goal for advancing human neuroprostheses. Current brain sensing research for prostheses via first clinical trials is offering tantalizing glimpses for the future, even if these technologies are cumbers...
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In acute experiments eight 5- to 24-wire-microelectrode arrays were inserted into the common peroneal nerve of the rat, to investigate whether the electrodes could selectively stimulate motor units of the extensor digitorum longus (EDL) muscle. Twitch-force-recruitment curves were measured from the EDL for each array electrode. The curves were plotted on a double-logarithmic scale and parameter...
متن کاملMicroelectrode arrays: application in batch-injection analysis
The application of microelectrode arrays in electrochemical batch-injection analysis, injection volumes 100 ml, has been investigated using a random array of microdisks (RAM) electrode made with carbon ®bres. Preliminary batch-injection experiments involving hexacyanoferrate(II) oxidation, using ®xed-potential amperometry and cyclic voltammetry, showed the expected lesser dependence on injectio...
متن کاملThe vesicular ATPase: A missing link between acidification and exocytosis
The vesicular adenosine triphosphatase (ATPase) acidifies intracellular compartments, including synaptic vesicles and secretory granules. A controversy about a second function of this ATPase in exocytosis has been fuelled by questions about multiple putative roles of acidification in the exocytic process. Now, Poëa-Guyon et al. (2013. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201303104) prese...
متن کاملTheoretical treatment and computer simulation of microelectrode arrays
New relations for and interrelations between the current responses of different microelectrode arrays are presented. Interdigitated microelectrode arrays (IDAs: alternating cathodes and anodes) and uniform microband electrode arrays (MEAs: only cathodes or anodes) are treated, and miniaturized systems with planar band electrodes or hemicylinder electrodes are discussed. A common basis was found...
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ژورنال
عنوان ژورنال: The Analyst
سال: 2015
ISSN: 0003-2654,1364-5528
DOI: 10.1039/c4an01932f